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Autism Male, 4 years old, October 2019

Summary

DiagnosisSexAgeNationality
AutismMale 4 yearsAustralian
InjectionsCell typeAdmission dateDischarge date
8UCMSC2019-10-072019-10-24

Condition On Admission

The patient had problems with social communication and social interaction including deficits in non-verbal communication, deficits in developing age appropriate friendships/ relationships and deficits in emotional reciprocity.

The patient  also has restricted, repetitive patterns of behaviour, interests or activities including:

  • highly restricted fixated interests that are abnormal in intensity and focus,
  • excessive adherence to routines, ritualised patterns of verbal or non-verbal behaviour or excessive resistance to change,
  • stereotyped or repetitive speech, motor movements or use of objects
  • Hyper- or hypo- reactivity to sensory input or unusual interest in sensory aspects of the environment.

Treatment Schedule

The patient received 8 umbilical cord mesenchymal stem cell (UCMSC) packets provided by intravenous (IV) way and intrathecal injections, as per the schedule below:

NumberDateCell TypeDelivery MethodSide Effects
12019-10-08UCMSCIntravenous Injectionnone reported
22019-10-11UCMSCIntrathecal Injection &
Intravenous Injection
none reported
32019-10-14UCMSCIntrathecal Injection &
Intravenous Injection
none reported
42019-10-18UCMSCIntrathecal Injection &
Intravenous Injection
none reported
52019-10-22UCMSCIntravenous Injectionnone reported

Condition 3 months after treatment

The patient’s mother mentioned the following: “My life as a mum has improved significantly. Our son loves playing with adults, however not with his peers….so there has been small improvement in terms of his peers as he now acknowledges his brother and sometimes is playful with him. He also looks at what other children are now doing (he didn’t care prior to stem cell treatment). Prior to the stem cell treatment  it was hard for me to have him with his brother together in the same room, now he is fine with his brother in the same room, same space, even a bit of play. Finally, before the treatment he would only sit for three minutes (max) during therapy sessions, now he does table top activities for up to an hour (with few breaks in between), he wants to learn”

Please see an excerpt from the patient’s 3 month assessment below:

SymptomParents’ Assessment of Improvement
Appropriate facial expressionsSmall improvements
Asking questionsNo improvement
Aware of dangerModerate improvement
Aware of environmentSignificant improvement
Bed wettingNo improvement
ConcentrationModerate improvement
Cooperation with othersModerate improvements
Dressing himselfNo improvement
Expressing own needsSmall improvements
General conversationNo improvement
General moodSignificant improvement
HyperactivityModerate improvement
Interaction with othersSmall improvement
Interest in othersModerate improvement
LethargyModerate improvement
Over/under eatingSmall improvement
Plays appropriatelySmall improvement
Repetitive movementsSmall improvement
Responding to commandsSignificant improvement
Rigidity in routineSmall improvement
Sleep disturbanceModerate improvement
Temper tantrumsSignificant improvement
Uses eye contactSignificant improvement
Uses greetingsModerate improvement