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Autism Male, 4 years old, October 2019

Summary

Diagnosis Sex Age Nationality
Autism Male 4 years Australian
Injections Cell type Admission date Discharge date
8 UCMSC 2019-10-07 2019-10-24

Condition On Admission

The patient had problems with social communication and social interaction including deficits in non-verbal communication, deficits in developing age appropriate friendships/ relationships and deficits in emotional reciprocity.

The patient  also has restricted, repetitive patterns of behaviour, interests or activities including:

  • highly restricted fixated interests that are abnormal in intensity and focus,
  • excessive adherence to routines, ritualised patterns of verbal or non-verbal behaviour or excessive resistance to change,
  • stereotyped or repetitive speech, motor movements or use of objects
  • Hyper- or hypo- reactivity to sensory input or unusual interest in sensory aspects of the environment.

Treatment Schedule

The patient received 8 umbilical cord mesenchymal stem cell (UCMSC) packets provided by intravenous (IV) way and intrathecal injections, as per the schedule below:

Number Date Cell Type Delivery Method Side Effects
1 2019-10-08 UCMSC Intravenous Injection none reported
2 2019-10-11 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
3 2019-10-14 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
4 2019-10-18 UCMSC Intrathecal Injection &
Intravenous Injection
none reported
5 2019-10-22 UCMSC Intravenous Injection none reported

Condition 3 months after treatment

The patient’s mother mentioned the following: “My life as a mum has improved significantly. Our son loves playing with adults, however not with his peers….so there has been small improvement in terms of his peers as he now acknowledges his brother and sometimes is playful with him. He also looks at what other children are now doing (he didn’t care prior to stem cell treatment). Prior to the stem cell treatment  it was hard for me to have him with his brother together in the same room, now he is fine with his brother in the same room, same space, even a bit of play. Finally, before the treatment he would only sit for three minutes (max) during therapy sessions, now he does table top activities for up to an hour (with few breaks in between), he wants to learn”

Please see an excerpt from the patient’s 3 month assessment below:

Symptom Parents’ Assessment of Improvement
Appropriate facial expressions Small improvements
Asking questions No improvement
Aware of danger Moderate improvement
Aware of environment Significant improvement
Bed wetting No improvement
Concentration Moderate improvement
Cooperation with others Moderate improvements
Dressing himself No improvement
Expressing own needs Small improvements
General conversation No improvement
General mood Significant improvement
Hyperactivity Moderate improvement
Interaction with others Small improvement
Interest in others Moderate improvement
Lethargy Moderate improvement
Over/under eating Small improvement
Plays appropriately Small improvement
Repetitive movements Small improvement
Responding to commands Significant improvement
Rigidity in routine Small improvement
Sleep disturbance Moderate improvement
Temper tantrums Significant improvement
Uses eye contact Significant improvement
Uses greetings Moderate improvement