Summary
| Diagnosis | Sex | Age | Nationality |
|---|---|---|---|
| Cerebral Palsy | Female | 2 years | Argentinia |
| Injections | Cell type | Admission date | Discharge date |
| 7 | UCBSC | 2012-03-03 | 2012-04-01 |
Condition On Admission
The patient was born with encephalopathy and had speech and movement development delays. The patient could not speak, sit, or walk upon admission to the hospital. She could move her limbs, but without any control. Muscle tone in both arms and legs was high.
Treatment Schedule
The patient received 7 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections as per schedule below:
| Number | Date | Cell Type | Delivery Method | Side Effects |
|---|---|---|---|---|
| 1 | 2012-03-05 | UCBSC | Intravenous Injection | none reported |
| 2 | 2012-03-07 | UCBSC | Intrathecal Injection | none reported |
| 3 | 2012-03-12 | UCBSC | Intrathecal Injection | none reported |
| 4 | 2012-03-16 | UCBSC | Intrathecal Injection | none reported |
| 5 | 2012-03-21 | UCBSC | Intrathecal Injection | none reported |
| 6 | 2012-03-23 | UCBSC | Intravenous Injection | none reported |
| 7 | 2012-03-28 | UCBSC | Intrathecal Injection | none reported |
Condition at discharge
The patient had no fever, headaches, or other side effects after transplantation of the stem cells. The doctors reported that the spasticity in her limbs had decreased, the movement of her right arm had become more controlled and flexible, and she had better overall body balance.
Condition 3 months after treatment
The patient’s parents completed the follow-up survey three months after the treatment; they commented that their daughter was now much more active and she had shown a big development in her speech. As for physical improvements, they observed that her trunk muscles had gained much more strength and she was now able to remain seated for longer periods. Her balance had also improved to the point where she was now able to stand with some support for longer periods of time. They felt their daughter’s quality of life had improved since the treatment. Please see the excerpt below from her 3 month follow-up survey (filled out by the patient’s parents):
| Symptom | Parents’ Assessment of Improvement |
| Trunk control | Significant improvement |
| Balance | Moderate improvement |
| Movement in general | Moderate improvement |
| Walking | Moderate improvement |
| Overall strength | Significant improvement |
| Limb muscle strength | Moderate improvements |
| Trunk muscle strength | Significant improvement |
| Range of movement | Moderate improvements |
| Fine motor control | Moderate improvements |
| Hand control | Moderate improvements |
| Speech | Significant improvement |
| General mental ability | Significant improvement |