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Case Study Cerebral Palsy Male, 6 years old, May 2012

Summary

Diagnosis Sex Age Nationality
Cerebral Palsy Male 6 years Argentinia
Injections Cell type Admission date Discharge date
6 UCBSC 2012-05-02 2012-06-01

Condition On Admission

The patient’s main presenting complaint was of a movement disorder and development delay since birth. The patient was conscious and his awareness and perceptive functions were normal. He was unable to speak. He could make some movements but was unable to fully control these. His four limbs were spastic.

Treatment Schedule

The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:

Number Date Cell Type Delivery Method Side Effects
1 2012-05-04 UCBSC Intravenous Injection none reported
2 2012-05-09 UCBSC Intrathecal Injection none reported
3 2012-05-14 UCBSC Intrathecal Injection none reported
4 2012-05-18 UCBSC Intrathecal Injection none reported
5 2012-05-23 UCBSC Intrathecal Injection none reported
6 2012-05-28 UCBSC Intrathecal Injection none reported

Condition at discharge

Following stem cell treatment, the patient had no fever, headache or other side effects. The doctors observed an improvement in his sitting balance and trunk control and they also noted his head control was better. The family reported small improvements in their son’s overall physical condition at the time of discharge. Below is an excerpt from the discharge improvement evaluation form filled by the patient’s parents:

Symptom Assessment of Improvement
Spasticity Small improvement
Trunk muscle strength Small improvement
Limb muscle strength Moderate improvement
Head Control Small improvement
Range of movement Small improvement
Involuntary movements Small improvement
Standing up Small improvement
Walking No improvement
Speech (babbling in infants) Small improvement
Swallowing Moderate improvement
Appetite Significant improvement
Learning disability Moderate improvement
Mood Moderate improvement

Condition 3 months after treatment

The family reported that their son had gained significant improvements in his quality of life. On the 3-month follow-up form they wrote: “He has improved head control, trunk control and mom and dad can now be said. He is now blowing and making objects with his hands with better control than before, he more firmly takes steps and has improved fine motor skills, now try to place small items in small containers.”

Please see as excerpt of his 3-month follow-up report (submitted by the patient’s parents):

Symptom Assessment of Improvement
Spasticity Significant improvement
Trunk muscle strength Moderate improvement
Limb muscle strength Significant improvement
Head Control Significant improvement
Range of movement Moderate improvement
Involuntary movements Moderate improvement
Balance Moderate improvement
Standing up Moderate improvement
Walking Moderate improvement
Speech (babbling in infants) Moderate improvement
Swallowing Moderate improvement
Appetite Significant improvement
Learning disability Significant improvement
Mood Significant improvement