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Case Study Cerebral Palsy Male, 6 years old, May 2012

Summary

DiagnosisSexAgeNationality
Cerebral PalsyMale 6 yearsArgentinia
InjectionsCell typeAdmission dateDischarge date
6UCBSC2012-05-022012-06-01

Condition On Admission

The patient’s main presenting complaint was of a movement disorder and development delay since birth. The patient was conscious and his awareness and perceptive functions were normal. He was unable to speak. He could make some movements but was unable to fully control these. His four limbs were spastic.

Treatment Schedule

The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:

NumberDateCell TypeDelivery MethodSide Effects
12012-05-04UCBSCIntravenous Injectionnone reported
22012-05-09UCBSCIntrathecal Injectionnone reported
32012-05-14UCBSCIntrathecal Injectionnone reported
42012-05-18UCBSCIntrathecal Injectionnone reported
52012-05-23UCBSCIntrathecal Injectionnone reported
62012-05-28UCBSCIntrathecal Injectionnone reported

Condition at discharge

Following stem cell treatment, the patient had no fever, headache or other side effects. The doctors observed an improvement in his sitting balance and trunk control and they also noted his head control was better. The family reported small improvements in their son’s overall physical condition at the time of discharge. Below is an excerpt from the discharge improvement evaluation form filled by the patient’s parents:

SymptomAssessment of Improvement
SpasticitySmall improvement
Trunk muscle strengthSmall improvement
Limb muscle strengthModerate improvement
Head ControlSmall improvement
Range of movementSmall improvement
Involuntary movementsSmall improvement
Standing upSmall improvement
WalkingNo improvement
Speech (babbling in infants)Small improvement
SwallowingModerate improvement
AppetiteSignificant improvement
Learning disabilityModerate improvement
MoodModerate improvement

Condition 3 months after treatment

The family reported that their son had gained significant improvements in his quality of life. On the 3-month follow-up form they wrote: “He has improved head control, trunk control and mom and dad can now be said. He is now blowing and making objects with his hands with better control than before, he more firmly takes steps and has improved fine motor skills, now try to place small items in small containers.”

Please see as excerpt of his 3-month follow-up report (submitted by the patient’s parents):

SymptomAssessment of Improvement
SpasticitySignificant improvement
Trunk muscle strengthModerate improvement
Limb muscle strengthSignificant improvement
Head ControlSignificant improvement
Range of movementModerate improvement
Involuntary movementsModerate improvement
BalanceModerate improvement
Standing upModerate improvement
WalkingModerate improvement
Speech (babbling in infants)Moderate improvement
SwallowingModerate improvement
AppetiteSignificant improvement
Learning disabilitySignificant improvement
MoodSignificant improvement