Summary
| Diagnosis | Sex | Age | Nationality |
|---|---|---|---|
| Cerebral Palsy | Male | 6 years | Argentinia |
| Injections | Cell type | Admission date | Discharge date |
| 6 | UCBSC | 2012-05-02 | 2012-06-01 |
Condition On Admission
The patient’s main presenting complaint was of a movement disorder and development delay since birth. The patient was conscious and his awareness and perceptive functions were normal. He was unable to speak. He could make some movements but was unable to fully control these. His four limbs were spastic.
Treatment Schedule
The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) and intrathecal injections, as per the schedule below:
| Number | Date | Cell Type | Delivery Method | Side Effects |
|---|---|---|---|---|
| 1 | 2012-05-04 | UCBSC | Intravenous Injection | none reported |
| 2 | 2012-05-09 | UCBSC | Intrathecal Injection | none reported |
| 3 | 2012-05-14 | UCBSC | Intrathecal Injection | none reported |
| 4 | 2012-05-18 | UCBSC | Intrathecal Injection | none reported |
| 5 | 2012-05-23 | UCBSC | Intrathecal Injection | none reported |
| 6 | 2012-05-28 | UCBSC | Intrathecal Injection | none reported |
Condition at discharge
Following stem cell treatment, the patient had no fever, headache or other side effects. The doctors observed an improvement in his sitting balance and trunk control and they also noted his head control was better. The family reported small improvements in their son’s overall physical condition at the time of discharge. Below is an excerpt from the discharge improvement evaluation form filled by the patient’s parents:
| Symptom | Assessment of Improvement |
| Spasticity | Small improvement |
| Trunk muscle strength | Small improvement |
| Limb muscle strength | Moderate improvement |
| Head Control | Small improvement |
| Range of movement | Small improvement |
| Involuntary movements | Small improvement |
| Standing up | Small improvement |
| Walking | No improvement |
| Speech (babbling in infants) | Small improvement |
| Swallowing | Moderate improvement |
| Appetite | Significant improvement |
| Learning disability | Moderate improvement |
| Mood | Moderate improvement |
Condition 3 months after treatment
The family reported that their son had gained significant improvements in his quality of life. On the 3-month follow-up form they wrote: “He has improved head control, trunk control and mom and dad can now be said. He is now blowing and making objects with his hands with better control than before, he more firmly takes steps and has improved fine motor skills, now try to place small items in small containers.” Please see as excerpt of his 3-month follow-up report (submitted by the patient’s parents):
| Symptom | Assessment of Improvement |
| Spasticity | Significant improvement |
| Trunk muscle strength | Moderate improvement |
| Limb muscle strength | Significant improvement |
| Head Control | Significant improvement |
| Range of movement | Moderate improvement |
| Involuntary movements | Moderate improvement |
| Balance | Moderate improvement |
| Standing up | Moderate improvement |
| Walking | Moderate improvement |
| Speech (babbling in infants) | Moderate improvement |
| Swallowing | Moderate improvement |
| Appetite | Significant improvement |
| Learning disability | Significant improvement |
| Mood | Significant improvement |