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Spina Bifida Male – 13 years – July 2012

Summary

Diagnosis Sex Age Nationality
Spina Bifida Male 13 years Serbia
Injections Cell type Admission date Discharge date
6 UCBSC 2012-07-02 2012-08-03

Condition On Admission

The doctor’s physical assessment of the patient upon admission found the patient had normal facial symmetry, sensation, and shoulder shrug. Motor neurological examinations showed an upper limbs score of 5 (full power), a proximal lower limbs score of 4, and a distal lower limbs score of 1. The coordinated movement of the upper limbs was normal but the patient could not move his legs at will. The patient could not move his feet but local muscle contraction could be observed. There was a loss of sensation in both ankles and around the tailbone and perineum. The loss of sensation in this area also caused a dysfunction of the sphincter of Oddi.

Treatment Schedule

The patient received 6 umbilical cord blood-derived stem cell (UCBSC) packets by intravenous (IV) injections as per schedule below.

Number Date Cell Type Delivery Method Side Effects
1 2012-07-04 UCBSC Intravenous Injection none reported
2 2012-07-09 UCBSC Intravenous Injection none reported
3 2012-07-13 UCBSC Intravenous Injection none reported
4 2012-07-18 UCBSC Intravenous Injection none reported
5 2012-07-23 UCBSC Intravenous Injection none reported
6 2012-07-27 UCBSC Intravenous Injection none reported

Condition at discharge

There were no remarkable changes in the patient’s condition during treatment.

Condition 1 month after treatment

One month following his treatment the patient’s family submitted his follow up assessment. They reported he had experienced good improvements in many symptom areas and that his quality of life had significantly improved. The patient himself described the major improvements he was experiencing as such: “I’m starting to feel the feet, and tingling from the knee down.”

Please see the excerpt below from their one month post-treatment assessment:

Symptom Family Own  Assessment of Improvement
Balance Moderate improvement
Movement in general Moderate improvement
Walking Moderate improvement
Standing up Moderate improvement
Overall strength Significant improvement
Limb muscle strength Moderate improvement
Trunk muscle strength Moderate improvement
Range of movement Significant improvement