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Seth – CP and ONH Stem Cell Patient

Seth was born in 2008 and was soon diagnosed with cerebral palsy (CP) and optic nerve hypoplasia (ONH). Seth received adult stem cell therapy in China to treat symptoms of CP and potentially improve his vision. Seth's grandmother sat with us for an interview in St Joseph, Missouri.
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References

  1. Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats
  2. Umbilical cord blood cells and brain stroke injury: bringing in fresh blood to address an old problem
  3. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
  4. Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum
  5. Li Huang, Che Zhang et al (2018). A Randomized, Placebo-Controlled Trial of Human Umbilical Cord Blood Mesenchymal Stem Cell Infusion for Children With Cerebral Palsy. Cell Transplantation (2018) Vol. 27(2) 325-334
  6. James E Carroll & Robert W Mays. Update on stem cell therapy for cerebral palsy. Expert Opin. Biol. Ther. (2011) 11.
  7. David T. Harris. Cord Blood Stem Cells: A Review of Potential Neurological Applications. Stem Cell Rev (2008) 4:269–274.
  8. F. Ramirez, ET AL. Umbilical Cord Stem Cell Therapy for Cerebral Palsy. Med Hypotheses RES 2006.3: 679-686.