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Zac – TBI and CP

Zac survived a tough accident for a little guy. A large security gate fell on him as a toddler and he suffocated beneath it. Doctors worked wonders bringing him back to life but he was left with a severe Traumatic Brain Injury. Since then he has been diagnosed with Cerebral Palsy. He has now traveled to China twice to receive adult stem cell transplants. In this interview his mother, Lorena, discusses his injury, condition and the improvements they've seen through the treatments. For patients like Zac, basic motor functions and eating disorders present real-life dangers and significant challenges to his care. Adult stem cell transplants cannot cure TBI. A damaged brain will not reform itself through the treatments. But a patient's quality of life can see real improvements.

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References

  1. Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats
  2. Umbilical cord blood cells and brain stroke injury: bringing in fresh blood to address an old problem
  3. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
  4. Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum
  5. Li Huang, Che Zhang et al (2018). A Randomized, Placebo-Controlled Trial of Human Umbilical Cord Blood Mesenchymal Stem Cell Infusion for Children With Cerebral Palsy. Cell Transplantation (2018) Vol. 27(2) 325-334
  6. F. Ramirez, ET AL. Umbilical Cord Stem Cell Therapy for Cerebral Palsy. Med Hypotheses RES 2006.3: 679-686.
  7. James E Carroll & Robert W Mays. Update on stem cell therapy for cerebral palsy. Expert Opin. Biol. Ther. (2011) 11.
  8. David T. Harris. Cord Blood Stem Cells: A Review of Potential Neurological Applications. Stem Cell Rev (2008) 4:269–274.