Stem Cell Treatment for Cerebral Palsy (CP)

A combination of stem cells and extensive therapies giving the patient real chances of improvement

Restoring Neurological Function
Using Stem Cells

Cerebral Palsy is a condition that results from a non-progressive insult to the developing brain in a child. The brain insult itself may occur for various reasons during fetus gestation, at birth or shortly after birth. Causes of cerebral palsy include intra-uterine infections such as toxoplasmosis and rubella,  restricted oxygen supply during birth (hypoxic ischemic encephalopathy), neonatal jaundice and more.

Cerebral Palsy can affect various parts of the brain and patients may not all have the same symptoms. Factors such as the severity of the original brain injury as well as the specific injured areas in the brain will determine the patient's symptoms. Patients diagnosed with cerebral palsy may experiences symptoms such as stiff muscles (hypertonia) or weak muscle function (hypotonia), poor coordination, tremors, impaired cognition, communication and sensory perception as well as behavorial abnomalities.

Few conventional treatment options are available for patients diagnosed with cerebral, which mostly focus on helping the patients to cope with their disability. However, none of them are actually treating the loss of neurological function caused by the original cerebral injury. Stem cells have the ability to regenerate injured cells in the body, helping to reverse the symptoms and allowing cerebral palsy patients to improve.

Why our Stem Cell Treatment is Effective

Since 2005, we have been developing comprehensive stem cell treatment protocols for cerebral palsy to overcome the limitations of conventional therapies. In our protocols, stem cells are combined with specialized therapies for cerebral palsy that not only focus on helping the patients to cope with their symptoms, but also treat the direct cause of the symptoms by promoting the healing of the brain injury. We believe that our comprehensive treatment approach for cerebral palsy gives our patients the best chances of improvements, allowing for a better quality of life.

Kaden's Stem Cell Journey

Due to complications at birth, Kaden was born premature and since the beginning diagnosed with Cerebral Palsy, ONH, and Apraxia of Speech. While receiving his 2nd stem cell treatment, Kaden and family share their improvements and hopes for the future.

Click here for more videos

Green Check tick symbol

What improvements from our treatment?

What improvements can be obtained from our treatment?

The purpose of our stem cell treatment is to restore neurological function in the brain/spinal cord lesion area, thus, various kinds of improvement are possible after our treatment and our past patients have experienced the following*:

  • Better balance and coordination
  • Reduced fatigue
  • Improved speech
  • Decreased tremors
  • Improved motor function
  • Better swallowing
  • Decreased neuropathic pain
  • Improved mental alertness

It is important to remember that, as for any medical treatment, improvements cannot be guaranteed. Please contact us for more information about the chances of improvement for a particular case.

Patient Stories

Blogs

Find out more about patients previously treated with Beike stem cell protocols. The families participating in these blog posts talk about their stories and present their own view of the treatment, including thoughts regarding the daily therapies, the stem cell injection themselves as well as improvement noticed during and after treatment.

More Patient Stories

Our Treatment Program in Details

Beike is unlike any other stem cell treatment provider in the world, the reason? Since 2005, we have been developing and optimizing our stem cell treatment protocols with the concept that only a very comprehensive solution can allow our patients to truly benefit from stem cells. We believe that stimulation through various therapies is necessary to enhance stem cell regenerative response, therefore our protocols include daily therapies to support the stem cells. Finally, we provide a wide variety and large quantities of stem cells in order to adapt to each patient specific condition and deliver maximized regenerative potential. Learn more about all the particularities that make our treatment truly comprehensive and unique.

  • 16 to 25 Days Stay
  • IV & Intrathecal Injections
  • UCBSC / UCMSC Cells
  • Daily Therapy Program
  • 120-400 Million Cells
  • Nutrition Program

The Stem Cell Therapy

Stem Cell Therapy

Our stem cell transplantation program for cerebral palsy consist in 6 to 8 simple and minimally invasive injections of umbilical cord derived stem cells. The stem cells are transplanted using two separate methods: by intravenous way using a standard IV drip system, and through intrathecal injection performed after lumbar puncture. These two delivery methods allow for increased efficacy while ensuring safety and minimum inconvenience for the patient. Read more about each procedure below:

Intravenous Injection (IV) >    Intrathecal Injection (LP) >

Acupuncture

Acupuncture

Acupuncture is a technique in which practitioners stimulate specific points on the body – most often by inserting thin needles through the skin. It is one of the most effective practices used in traditional Chinese medicine. Acupuncture stimulates nerve fibers to transmit signals to the spinal cord and brain, activating the body’s central nervous system. The spinal cord and brain then release hormones responsible for making us feel less pain while improving overall health. Acupuncture may also: increase blood circulation and body temperature, affect white blood cell activity (responsible for our immune function), reduce cholesterol and triglyceride levels, and regulate blood sugar levels.

Aquatherapy

Aquatherapy

Aquatic Physical Therapy is the practice of physical therapy in a specifically designed water pool with a therapist. The unique properties of the aquatic environment enhance interventions for patients with neurological or musculoskeletal conditions. Aquatic therapy includes a wide range of techniques allowing patients to improve their balance, muscle strength and body mechanics. Aquatic therapy works to enhance the rehabilitation process and support effectiveness of stem cell treatment.

Hyperbaric Oxygen Therapy

Hyperbaric Oxygen Therapy

Hyperbaric Oxygen Therapy (HBOT) is the medical use of oxygen at a level higher than atmospheric pressure. The equipment required consists of pressure chamber, which may be of rigid or flexible construction, and a means of delivering 100% oxygen into the respiratory system. Published research shows that HBOT increases the lifespan of stem cells after injection and provides an oxygen-rich atmosphere for the body to function at optimum levels.

Nutrition Therapy

Nutrition Therapy

Medical nutrition therapy (MNT) is a therapeutic approach to treat medical conditions and their associated symptoms via the use of a specifically tailored diet devised and monitored by a specialist. The therapy aims at fixing nutritional deficiencies and physiological imbalances in order to provide the best environment possible for the stem cells to develop properly as well as improving patient’s general health.

Nutritional healthy plate of food

Transcranial Magnetic Stimulation

Transcranial Magnetic Stimulation

Research has shown that TMS can effectively treat symptoms of depression, anxiety, neurological pain, stroke, spinal cord injuries, autism and more. This procedure is very simple and noninvasive. During the procedure, a magnetic field generator or “coil” is placed near the head of the person receiving the treatment. The coil produces small electrical currents in the region of the brain just under the coil via electromagnetic induction. This electrical field causes a change in the transmembrane current of the neuron which leads to depolarization or hyperpolarization of the neuron and the firing of an action potential.

Occupational Therapy

Occupational Therapy

Occupational therapy interventions focus on adapting the environment, modifying the task and teaching the skill, in order to increase participation in and performance of daily activities, particularly those that are meaningful to the patient with physical, mental, or cognitive disorders. Our Occupational Therapists also focus much of their work on identifying and eliminating environmental barriers to independence and participation in daily activities, similar to everyday life.

Physiotherapy

Physiotherapy

Physical therapy or physiotherapy (often abbreviated to PT) is a physical medicine and rehabilitation specialty that, by using mechanical force and movements, remediates impairments and promotes mobility, function, and quality of life through examination, diagnosis, prognosis, and physical intervention. We combine our PT with stem cells for maximum physical rehabilitation improvements.

Nerve Growth Factor (NGF)

Nerve Growth Factor (NGF)

Nerve growth factor (NGF) is a member of the neurotrophic factor (neurotrophin, NTFS) family, which can prevent the death of nerve cells and has many features of typical neurotransmitter molecules. NGF plays an important role in the development and growth of nerve cells. NGF is synthesized and secreted by tissues (corneal epithelial, endothelial, and corneal stromal cells), and it can be up-taken by sympathetic or sensory nerve endings and then transported to be stored in neuronal cell bodies where it can promote the growth and differentiation of nerve cells.

NGF can exert neurotrophic effects on injured nerves and promote neurogenesis (the process of generating neurons from stem cells) that is closely related to the development and functional maintenance and repair of the central nervous system. It is also capable of promoting the regeneration of injured neurons in the peripheral nervous system, improving the pathology of neurons and protecting the nerves against hypoxia (lack of oxygen)/ischemia (lack of blood supply).

Stem Cell Quality and Quantity Ensured

Packaging for Beike Biotechnology Stem Cell products

Different types of stem cells for different needs

Beike provides stem cells from two separate sources: umbilical cord blood and umbilical cord tissue. Umbilical cord related samples are donated by healthy mothers after normal births and are sent to Beike Biotech's laboratories for processing.
After reviewing the patient’s full medical information, our doctors will recommend which source of stem cells should be used for treatment. Our treatment protocols may include one or multiple types of stem cell in combination depending on each patient's specific condition.

more

Highest International Stem Cell Processing Standards

Beike Biotechnology is processing its own adult stem cells in its internationally accredited laboratories. The company has full control over the processing and quality control of all stem cell products, ensuring perfect safety and highest quality. Processing methods and facility are accredited by the American Association of Blood Banks (AABB), the highest international standard in the industry.

more

American Association of Blood Banks AABB accreditation logo

Patient Videos

Below are video interviews recorded during treatment with Beike stem cells. The families showcased in these videos talk about their personal stories and their experience of the treatment including the improvement noticed. The improvements mentioned in these videos are typical, however it does not guarantee that all patients may have the same improvements.

Subscribe to our video channels 

 

Why Choose Beike?

Experience: With more than a decade of practice, you are ensured to be advised and treated by competent professionals.

Safety: Accredited by the American Association of Blood Banks (AABB) and following highest international standards, our stem cell processing methods and laboratories ensure that you receive the best stem cell quality available.

Diversity: Multiple types of stem cells having different capabilities are available to adapt to each patient's specific condition. We do not use the same type of stem cells for all patients.

Extensiveness: A complete supportive therapy program is provided daily to stimulate patient's freshly transplanted stem cells. The best improvement can only be obtain by supporting your stem cells.

Support: A full follow-up program is provided after the treatment and you will be asked to take part in it at 1, 3, 6 and 12 months after treatment. Access to our team after the treatment is very important as you may receive further advice to maximize improvements.

Beike Biotechnology head office building located in Shenzhen China

Learn More About Us

Founded in July 2005, Shenzhen Beike Biotechnology Co. Ltd. (hereinafter referred to as Beike Biotechnology) is a national high-tech enterprise specialized in clinical transformation and technical service of biological treatment technology of strategic emerging industries.

Get more information now

Please include your country code in the phone number
If your diagnosis is not listed, please select 'other'.

More About Cerebral Palsy

What is cerebral palsy?
Cerebral palsy – also known as CP – is a group of conditions defined as impairment in motor function, that appear in early stages of childhood, with CP affecting approximately 2 in every 1000 live births1. Symptoms of children with cerebral palsy often include:

  • Stiff muscles – also known as hypertonia
  • Poor coordination
  • Tremors
  • Weak muscle function – also known as hypotonia

Issues with impaired cognition, communication, and sensory perception, as well as behavioral abnormalities.

What causes CP?
CP results from a non-progressive insult to the developing brain in a child. CP is the clinical presentation of a wide variety of cerebral cortical or sub-cortical insults occurring either intra-uterine, or during the first year of life. Although the cause of CP in around half of all patients often remains unknown, CP is known to result from intra-uterine infections such as toxoplasmosis and rubella, as well as restricted oxygen supply during birth, known as hypoxic ischemic encephalopathy (HIE). It is also thought that a small proportion of CP cases result from the inheritance of various defective genes, such as glutamate decarboxylase-1, with such genes associating with the correct development of the brain. In addition to genetic factors, neonatal jaundice has also been demonstrated to result in CP, due to a buildup of bilirubin within the brain resulting in a condition known as kernicterus.

How is CP diagnosed?
Diagnosis of CP is often made when physicians notice delays in developmental milestones reached by patients. Infants with CP may not roll or smile as early as other children and may struggle to walk. Diagnosis is made primarily on physical examination of the patient, although some specialists may perform additional investigations such as CT and MRI scans. Once a diagnosis of CP is made, the condition can be further classified according to the symptoms the patient is exhibiting. These classifications include:

  • Ataxic CP: occurs in 5-10% of all cases of CP and results from damage to the cerebellum, a specific area of the brain involved in coordination. As a result, patients exhibit difficulties in coordinating movements, in particular, in their arms, legs and chest. In addition, individuals with CP often develop an intention tremor when
  • Spastic CP: is the most common type of CP and is associated with prematurity. An area in the brain known as the periventricular germinal matrix, which is a region of active neuronal proliferation, is particularly susceptible to bleeding and hypoxic ischemic injury. It is therefore this area that is damaged in spastic CP. Patients with spastic CP develop stiff muscles, also known as hypertonia.
  • Athethoid CP: is also known as dyskinetic CP and results from damage to structures located within the base of the brain, often results from hypoxic injury or kernicterus. Patients with athethoid CP develop both hyper- and hypotonia and may develop contractions within muscles throughout the body.

What are the current conventional treatments for CP?
Current treatments for CP are limited and primarily focus on symptomatic relief, with medications routinely prescribed to reduce painful muscle spasms. To date, there are no treatments licensed for use by the FDA which reverse the symptoms of CP.

Aside from medication, the mainstay treatment for CP often centers on physiotherapy programs, which are designed in order to help build tone and strength in patients, as well as helping limit spasms in patients with spastic CP. In addition to physiotherapy, occupational therapy also plays an important role

It is clear, therefore, that new treatments for CP are much needed. Stem cell therapy has offered promise that administration of patient-derived stem cells may help in the treatment and management of CP. Beike are now offering this revolutionary treatment for CP, which has been shown to improve symptom control in patients.

What are the current stem cell-based treatments for cerebral palsy?
Stem cells are multipotent cells that have been shown to have regenerative capacity in a variety of conditions, as well as stimulating growth and modulation of the immune system. It is thought that by injecting stem cells into the spinal column, these cells will enter the brain and generate new neuronal growth and therefore aid in the reduction of symptoms exhibited by CP patients.

To date, several clinical studies have examined the use of stem cells for the treatment of cerebral palsy. These have included:

  • A study by Chahine et al.1 in 2016, administered stem cells derived from the bone marrow, known as bone marrow mononuclear cells, to seventeen patients with CP using intrathecal injections. All patients had an uneventful post-injection course with 73% of the evaluable patients treated having a good response using the Gross Motor Function Classification System (GMFCS). The average improvement was 1.3 levels on the GMFCS with patients also demonstrating cognitive improvements as well. These findings suggest that intrathecal injection of stem cells may produce improvements in patients with CP.
  • A more recently study by Nguyen et al.2 in 2017, also injected bone marrow mononuclear cells into patients with CP in two separate treatments at three and six months. The study showed that gross motor function was markedly improved 3 months or 6 months after stem cell transplantation than at baseline.

These studies therefore clearly show that stem cells offer an effective and safe treatment for CP.