What is Spina Bifida?
During a fetus’ development in the womb, there is a group of cells called the neural tube that are responsible for forming the spinal cord and the brain.1 Typically, this should close during development and then be covered by the spine bone to protect the delicate spinal cord. Sometimes, however, it does not close all the way, causing the back bone to be incomplete.2
Children with spina bifida may experience other symptoms such as apnea, in which the child can forget to breathe, along with other respiratory problems, incontinence in the bladder and bowels, paralysis in the lower extremities, developed curves in the spine, and talipes (or clubfoot) which results in malformed or underdeveloped feet.3 Another common side effect, and sometimes what alerts parents to the problem, is hair growth or a dimple (sacral dimple) around the site of the spinal cord opening. This site is called the occulta, meaning “hidden” as the skin covers the spinal opening.4
There are three main types of spina bifida:
- Spina bifida occulta (SBO): This is both the most common and most mild form of spina bifida. Also known as “hidden spina bifida,” many people will not even be aware that they have it until they have an X-ray for other reasons because it often does not have symptoms.
- Meningocele: A sac of spinal fluid pushes through an opening in the back. This can have little to no symptoms, or create problems with continence in the bladder and bowels.
- Myelomeningocele: This is the most severe form of spina bifida, as there may be multiple locations in the spine that have openings with sacs of spinal fluid poking out. Unlike meningocele, these sacs of spinal fluid also contain part of the spinal cord and nerves, which are usually damaged.
Matheus’ Stem Cell Journey
Matheus was born with his spine open due to spina bifida (myelomeningocele) and during the subsequent procedure to correct it suffered hydrocephalus and Arnold Chiari malformation. However after undergoing stem cell treatment the improvements have been “countless” in the words of his mother.
Find out more about patients previously treated with Beike stem cell protocols. The families participating in these blog posts talk about their stories and present their own view of the treatment, including thoughts regarding the daily therapies, the stem cell injection themselves as well as improvement noticed during and after treatment.
Matheus was born with his spine open due to spina bifida (myelomeningocele) and during the subsequent procedure to correct it suffered hydrocephalus and Arnold Chiari malformation. However after undergoing spina bifida stem cell treatment the improvements have been “countless” in the words of his mother. Within a week they have … read more
Ischemic stroke is the most common form of stroke, caused by a narrowing or blockage of blood flow in the brain. As a result of this lack of blood flow, cells begin to die and this can cause irreparable damage. When Ana had an ischemic stroke a few years ago, … read more
⏲️ 4 mins read Lorenzo was born in Brazil mid-November 2014 with only 28 weeks of gestation. Due to extreme prematurity, he had a brain injury called periventricular leukomalacia, which boils down to brain necrosis – as if part of his brain had died. He was admitted to the neonatal … read more
Our Treatment Program in Details
Beike is unlike any other stem cell treatment provider in the world, the reason? Since 2005, we have been developing and optimizing our stem cell treatment protocols with the concept that only a very comprehensive solution can allow our patients to truly benefit from stem cells. We believe that stimulation through various therapies is necessary to enhance stem cell regenerative response, therefore our protocols include daily therapies to support the stem cells. Finally, we provide a wide variety and large quantities of stem cells in order to adapt to each patient specific condition and deliver maximized regenerative potential.
Our stem cell therapy program for spina bifida consist in 6 to 8 simple and minimally invasive injections of umbilical cord derived stem cells. The stem cells are transplanted using two separate methods: by intravenous way using a standard IV drip system, and through intrathecal injection performed after lumbar puncture. These two delivery methods allow for increased efficacy while ensuring safety and minimum inconvenience for the patient.
- 15 to 23 Days Stay
- IV & Intrathecal Injections
- UCBSC / UCMSC Cells
- Daily Therapy Program
- 120-400 Million Cells
- Nutrition Program
Stem Cell Quality and Quantity Ensured
Different types of stem cells for different needs
Beike provides stem cells from two separate sources: umbilical cord blood and umbilical cord tissue. Umbilical cord related samples are donated by healthy mothers after normal births and are sent to Beike Biotech’s laboratories for processing.
After reviewing the patient’s full medical information, our doctors will recommend which source of stem cells should be used for treatment. Our treatment protocols may include one or multiple types of stem cells in combination depending on each patient’s specific condition.
Highest International Stem Cell Processing Standards
Beike Biotechnology is processing its own adult stem cells in its internationally accredited laboratories. The company has full control over the processing and quality control of all stem cell products, ensuring perfect safety and highest quality. Processing methods and facility are accredited by the American Association of Blood Banks (AABB), the highest international standard in the industry.
Below are video interviews recorded during treatment with Beike stem cells. The families showcased in these videos talk about their personal stories and their experience of the treatment including the improvement noticed. The improvements mentioned in these videos are typical, however it does not guarantee that all patients may have the same improvements.
Why Choose Beike?
Experience: With more than a decade of practice, you are ensured to be advised and treated by competent professionals.
Safety: Accredited by the American Association of Blood Banks (AABB) and following highest international standards, our stem cell processing methods and laboratories ensure that you receive the best stem cell quality available.
Diversity: Multiple types of stem cells having different capabilities are available to adapt to each patient’s specific condition. We do not use the same type of stem cells for all patients.
Extensiveness: A complete supportive therapy program is provided daily to stimulate patient’s freshly transplanted stem cells. The best improvement can only be obtain by supporting your stem cells.
Support: A full follow-up program is provided after the treatment and you will be asked to take part in it at 1, 3, 6 and 12 months after treatment. Access to our team after the treatment is very important as you may receive further advice to maximize improvements.
Learn More About Us
Founded in July 2005, Shenzhen Beike Biotechnology is a national high-tech enterprise specialized in clinical transformation and technical service of biological treatment technology of strategic emerging industries.
Get more information now
More about Spina Bifida
90% of spina bifida cases are discovered during an ultrasound before 18 weeks of pregnancy. Diagnosis is commonly done through a blood screening to test for alpha-fetoprotein (AFP) in the mother’s blood. Babies create this AFP protein that commonly reaches the mother’s bloodstream, but if the level of AFP is too high it could be a sign of spina bifida.
To determine the reason for high levels of AFP, a doctor will have an ultrasound done to confirm the reason. If further testing is needed, a doctor can perform an amniocentesis test in which a part of the amniotic fluid surrounding the baby is tested. If that fluid has a high concentration of AFP as well, it could be because the skin that should cover the spinal cord is not there and is causing a leakage of the baby’s spinal fluid.11
When a mother learns that her baby has spina bifida, an in depth diagnosis is conducted to determine exactly how severe the spina bifida is for the child, and what treatment options are available or necessary. After a complete diagnosis, the mother can choose if she wants to terminate the pregnancy or proceed with or without treatment. A common method of treatment is to have prenatal surgery. During this surgery, the neurosurgeon will remove the abnormal sac of skin from the nerve tissue, then moves the exposed nerve tissue back into the spinal canal.14 However, if for whatever reason the mother does not choose to have fetal surgery, babies born with spina bifida can still have postnatal surgery. The surgery is almost exactly the same and with the same goal, just done later for what could be a combination of medical and personal reasons. Mothers will typically have a cesarean section birth so as not to risk further damage to the child and keep the myelomeningocele intact, and surgery will be done within the first two days of the child’s life.15
If the child suffers from hydrocephalus, which is common among myelomeningocele patients, doctors will often insert a shunt tube, which will drain fluid from the brain into the abdomen, which can then absorb the fluid. This can help with the symptoms of hydrocephalus, but can have its own complications and will often need to be replaced multiple times throughout a patient’s life.